The Neuropilin-1 (NRP1) Monoclonal Antibody is a cutting-edge research tool designed for the study of neuropilin-1, a transmembrane receptor involved in a wide range of biological processes, including cell migration, angiogenesis, and immune response modulation. This monoclonal antibody, developed through rigorous testing and validation, specifically targets the NRP1 protein and is optimized for use in various research applications, such as immunofluorescence and flow cytometry.Neuropilin-1 is a critical player in tumor development, making this antibody a valuable tool for cancer research. Its expression on immune cells also suggests a role in immune regulation, opening up avenues for exploration in immunology and autoimmune disease studies.
By enabling precise detection and analysis of NRP1 in different cell types and tissues, this antibody empowers researchers to uncover new insights into the function and significance of neuropilin-1 in health and disease.With its high specificity, sensitivity, and reproducibility, the Neuropilin-1 Monoclonal Antibody from Assay Genie is a reliable choice for scientists seeking to deepen their understanding of NRP1 biology and its potential as a therapeutic target in various pathological conditions. Order yours today and advance your research with confidence.
Product Name:
Neuropilin-1 (NRP1) Monoclonal Antibody
SKU:
CAB22213
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-644 of human Neuropilin-1 (NRP1) (NP_003864.5).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
68kDa/71kDa/103kDa
Observed MW:
120-135kDa
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
Purification Method:
Affinity purification
Gene ID:
8829
Clone Number:
ARC55415
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of A-549, using Neuropilin-1 (NRP1) antibody (CAB22213) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:200000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
