The Neuromodulin Polyclonal Antibody (CAB6376) is a valuable tool for researchers investigating neuromodulin, a protein involved in neuronal function and plasticity. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in a variety of applications, including Western blot and immunohistochemistry.Neuromodulin, also known as growth associated protein-43 (GAP-43), is essential for neural development, synaptic plasticity, and nerve regeneration. Studies have shown its involvement in learning and memory, as well as in neurological conditions like Alzheimer's disease and traumatic brain injury.
The Neuromodulin Polyclonal Antibody enables precise detection and analysis of neuromodulin levels in different cell types, making it an invaluable tool for research in neuroscience and neurology.With its ability to target neuromodulin, this antibody opens up possibilities for exploring the role of this protein in neuronal signaling, plasticity, and regeneration. By understanding the function of neuromodulin, researchers can gain insights into mechanisms underlying brain function and disorders, paving the way for potential therapeutic interventions targeting neurological conditions.
Product Name:
GAP43 Rabbit Polyclonal Antibody
SKU:
CAB6376
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human GAP43 (NP_002036.1).
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2596
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GAP43 antibody (CAB6376) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
