NRGN Rabbit Polyclonal Antibody (CAB8444)
- SKU:
- CAB8444
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
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Description
Product Name: | NRGN Rabbit Polyclonal Antibody |
SKU: | CAB8444 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-78 of human NRGN (NP_001119653.1). |
Sequence: | MDCC TENA CSKP DDDI LDIP LDDP GANA AAAK IQAS FRGH MARK KIKS GERG RKGP GPGG PGGA GVAR GGAG GGPS GD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RC3; hng; NRGN |
Positive Sample: | PC-3,U-251MG,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | axon, cytosol, dendritic spine head, glutamatergic synapse, nucleus, postsynaptic density, postsynaptic membrane |
Calculated MW: | 8kDa |
Observed MW: | 14kDa |
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
Purification Method: | Affinity purification |
Gene ID: | 4900 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |