The Neuroglobin Polyclonal Antibody (CAB6477) offered by Assay Genie is a vital tool for researchers studying neuroglobin, a protein that plays a crucial role in the brain's response to ischemia and neurodegeneration. This antibody is raised in rabbits and has been validated for use in a variety of applications, including Western blotting and immunohistochemistry.Neuroglobin is a globin protein predominantly found in neurons, where it acts as a cytoprotective molecule against oxidative stress and hypoxic conditions. Studies have shown that neuroglobin can protect against neuronal cell death and promote cell survival in various neurological disorders, making it a promising target for therapeutic interventions.
By using the Neuroglobin Polyclonal Antibody, researchers can effectively detect and analyze neuroglobin expression in different cell types and tissues, providing valuable insights into its role in neuroprotection and neurodegenerative diseases. This antibody is essential for advancements in neuroscience and the development of potential treatments for conditions such as stroke, Alzheimer's disease, and Parkinson's disease.Overall, the Neuroglobin Polyclonal Antibody from Assay Genie is an indispensable tool for scientists investigating the functions and therapeutic potential of neuroglobin in neurology and related fields.
Product Name:
NGB Rabbit Polyclonal Antibody
SKU:
CAB6477
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-151 of human NGB (NP_067080.1).
This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.
Purification Method:
Affinity purification
Gene ID:
58157
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using NGB Rabbit pAb (CAB6477) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
