The Neurog3 Polyclonal Antibody (CAB21523) is a valuable tool for researchers studying the Neurog3 protein, a key transcription factor involved in the development of pancreatic endocrine cells. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to Neurog3, this antibody enables precise detection and analysis of this crucial protein in a variety of cell types.Neurog3 is essential for the differentiation of endocrine cells in the pancreas, making it a promising target for research into diabetes and other pancreatic disorders.
By understanding the role of Neurog3 in pancreatic development, researchers may uncover new insights into the pathogenesis of these diseases and potentially identify novel therapeutic strategies.Overall, the Neurog3 Polyclonal Antibody is a reliable tool for investigating the function of Neurog3 in pancreatic development and disease, with the potential to advance our understanding of endocrine cell biology and inform future therapeutic approaches.
Product Name:
NEUROG3 Polyclonal Antibody
SKU:
CAB21523
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 144-214 of human NEUROG3 (NP_066279.2).
Mouse large intestine,Mouse small intestine,Mouse pancreas
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
23kDa
Observed MW:
Refer to figures
The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
Purification Method:
Affinity purification
Gene ID:
50674
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NEUROG3 Rabbit pAb (CAB21523) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
