The Neurog3 Polyclonal Antibody (CAB16526) is a valuable tool for researchers studying Neurog3, a transcription factor essential for the development of endocrine cells in the pancreas and intestine. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blotting. By specifically binding to the Neurog3 protein, this antibody enables the detection and analysis of Neurog3 expression in various cell types, making it ideal for studies in developmental biology and diabetes research.Neurog3 is a key regulator of endocrine cell differentiation, playing a crucial role in the production of hormones such as insulin and glucagon.
Dysfunction of Neurog3 has been linked to disorders like diabetes, highlighting its importance in pancreatic development and function. By investigating the role of Neurog3, researchers can gain insights into the mechanisms underlying endocrine cell formation and potential therapeutic targets for metabolic diseases. The Neurog3 Polyclonal Antibody offers a reliable tool for investigating the function and regulation of Neurog3 in these contexts.
Product Name:
NEUROG3 Rabbit Polyclonal Antibody
SKU:
CAB16526
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 144-214 of human NEUROG3 (NP_066279.2).
The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
Purification Method:
Affinity purification
Gene ID:
50674
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat large intestine, using NEUROG3 Rabbit pAb (CAB16526) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
