The NeuroD1 Polyclonal Antibody (CAB16927) is a valuable tool for researchers studying NeuroD1, a transcription factor essential for neuronal differentiation and development. This antibody, raised in rabbits, is highly specific and sensitive for detecting NeuroD1 protein expression in human samples. Validated for use in Western blot and immunohistochemistry applications, it allows for precise and accurate analysis of NeuroD1 in various cell types and tissues.NeuroD1, also known as beta-2, is a key regulator of neurogenesis and plays a crucial role in the formation of neurons in the central nervous system.
Dysregulation of NeuroD1 has been linked to various neurological disorders, making it a promising target for therapeutic interventions. By understanding the function and expression of NeuroD1, researchers can gain insights into neuronal development, neurodegenerative diseases, and potential therapeutic strategies for neurologic conditions.
Product Name:
NEUROD1 Rabbit Polyclonal Antibody
SKU:
CAB16927
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-356 of human NEUROD1 (NP_002491.2).
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
Purification Method:
Affinity purification
Gene ID:
4760
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded mouse brain using NEUROD1 Rabbit pAb (CAB16927) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
