The NeuroD1 Polyclonal Antibody (CAB1147) is a specialized tool for studying NeuroD1, a transcription factor essential for neuronal development and differentiation. This antibody, produced by immunizing rabbits, exhibits strong reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.NeuroD1, also known as Beta2, is a key player in the formation of neuronal circuits and the regulation of gene expression in the nervous system. Its crucial role in neurogenesis and neuronal maturation makes it a valuable target for investigating neurological disorders and developmental abnormalities.
By detecting and analyzing NeuroD1 protein expression, researchers can gain insights into the mechanisms underlying neuronal development and function.The NeuroD1 Polyclonal Antibody enables precise detection of NeuroD1 in different cell types and tissues, offering a valuable tool for studies in neuroscience and developmental biology. Its ability to specifically bind to NeuroD1 protein makes it an essential resource for unraveling the complex pathways involved in neuronal differentiation and function.
Product Name:
NEUROD1 Rabbit Polyclonal Antibody
SKU:
CAB1147
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-356 of human NEUROD1 (NP_002491.2).
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
Purification Method:
Affinity purification
Gene ID:
4760
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using NEUROD1 Rabbit pAb (CAB1147) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
