The NeuroD1 Monoclonal Antibody is a powerful tool for researchers studying NeuroD1, a transcription factor crucial for the development of neuronal cells. This antibody is specifically designed to target NeuroD1 and is highly reactive with human samples, making it ideal for use in various research applications like immunohistochemistry and flow cytometry. By binding to NeuroD1, this antibody enables the detection and analysis of NeuroD1 protein levels in different cell types, providing valuable insights into neurogenesis and neuronal development.NeuroD1, also known as Neurogenic Differentiation 1, plays a key role in neuronal differentiation and maturation, making it a key player in neurodevelopmental processes.
Dysregulation of NeuroD1 has been implicated in various neurological disorders, making it a promising target for research aimed at understanding and potentially treating conditions like Alzheimer's disease, Parkinson's disease, and epilepsy. By studying NeuroD1 activity, researchers can gain a better understanding of neurodevelopment and potentially identify new therapeutic targets for neurological disorders.
Product Name:
NeuroD1 Monoclonal Antibody
SKU:
CAB12020
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NeuroD1 (NP_002491.2).
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
Purification Method:
Affinity purification
Gene ID:
4760
Clone Number:
ARC0483
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using NeuroD1 Rabbit mAb (CAB12020) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
