NCALD Rabbit Polyclonal Antibody (CAB8000)
- SKU:
- CAB8000
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | NCALD Rabbit Polyclonal Antibody |
SKU: | CAB8000 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human NCALD (NP_114430.2). |
Sequence: | MGKQ NSKL RPEV MQDL LEST DFTE HEIQ EWYK GFLR DCPS GHLS MEEF KKIY GNFF PYGD ASKF AEHV FRTF DANG DGTI DFRE FIIA LSVT SRGK LEQK LKWA FSMY DLDG NGYI SKAE MLEI VQAI YKMV SSVM KMPE DEST PEKR TEKI FRQM DTNR DGKL SLEE FIRG AKSD PSIV RLLQ CDPS SAGQ F |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NCALD |
Positive Sample: | A-549,THP-1,BT-474,Mouse brain,Mouse liver,Mouse lung,Mouse spinal cord,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | clathrin coat of trans-Golgi network vesicle, cytosol |
Calculated MW: | 22kDa |
Observed MW: | 22kDa |
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 83988 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |