The Neun Monoclonal Antibody (CAB19086) is a powerful tool designed for research involving the neuronal protein Neun, also known as Fox-3. This rabbit monoclonal antibody is highly specific and sensitive for Neun in human samples, making it an ideal choice for Western blot applications. Neun is a neuron-specific RNA-binding protein that plays a critical role in neuronal development and function. It is commonly used as a marker for post-mitotic neurons in various research applications, including neuroscience, neurodegenerative diseases, and brain development studies.
By targeting Neun, researchers can accurately detect and analyze neuronal populations in a variety of cell types, providing valuable insights into neuronal activity and function. This antibody's high specificity and sensitivity make it a valuable tool for studying the role of Neun in neuronal development, neurogenesis, and neurodegenerative disorders. Overall, the Neun Monoclonal Antibody (CAB19086) is a reliable and versatile tool for researchers seeking to explore the complex mechanisms underlying neuronal function and dysfunction.
Product Name:
NeuN Rabbit Monoclonal Antibody
SKU:
CAB19086
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NeuN (A6NFN3).
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
146713
Clone Number:
ARC0202
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using NeuN Rabbit mAb (CAB19086) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
