The Neu3 Polyclonal Antibody (CAB13842) is a valuable tool for researchers studying the Neu3 protein, which plays a key role in regulating sialic acid content on cell surfaces. This antibody is raised in rabbits and is highly specific for human samples, making it ideal for use in Western blot applications to detect and analyze Neu3 expression.Neu3 is a critical enzyme involved in the turnover of sialic acids, which are important for cell-cell interactions, signal transduction, and immune recognition. Dysregulation of sialic acid levels has been linked to various diseases, including cancer, inflammation, and neurodegenerative disorders.
By targeting Neu3, researchers can gain insights into the mechanisms underlying these conditions and explore potential therapeutic interventions.This polyclonal antibody offers high sensitivity and specificity, enabling accurate detection of Neu3 in a variety of cell types and tissues. Its versatility makes it a valuable tool for studies in molecular biology, biochemistry, and disease pathology. Researchers can use this antibody to further our understanding of Neu3 function and its implications for human health.
Product Name:
NEU3 Rabbit Polyclonal Antibody
SKU:
CAB13842
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 222-461 of human NEU3 (NP_006647.3).
This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer.
Purification Method:
Affinity purification
Gene ID:
10825
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NEU3 Rabbit pAb (CAB13842) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
