The NET1 Polyclonal Antibody (CAB1213) is a valuable tool for studying the NET1 protein, an important regulator of cell migration and invasion. This antibody, derived from rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the NET1 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for research in cancer biology and metastasis.NET1, also known as neuroepithelial cell-transforming gene 1, plays a crucial role in controlling cell motility and promoting tumor progression.
Its involvement in cancer metastasis and invasion makes it a promising target for understanding and potentially targeting aggressive cancer phenotypes. By investigating the functions of NET1, researchers can gain insights into the molecular mechanisms underlying cancer spread and identify potential therapeutic strategies to inhibit tumor progression.
Product Name:
NET1 Rabbit Polyclonal Antibody
SKU:
CAB1213
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NET1 (NP_001040625.1).
This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
10276
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NET1 antibody (CAB1213) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
