The Nestin Polyclonal Antibody (CAB11861) is a valuable tool for researchers studying Nestin, a type VI intermediate filament protein that is commonly used as a marker for neural stem cells. This antibody, generated in rabbits, has high reactivity with human samples and is validated for use in various applications, including Western blot and immunofluorescence.Nestin is a key protein involved in neurogenesis and is critical for maintaining the self-renewal and multipotency of neural stem cells. By targeting Nestin with this antibody, researchers can accurately detect and analyze the distribution and expression levels of Nestin in different cell types, making it an essential tool for studies in neuroscience, developmental biology, and regenerative medicine.
The Nestin Polyclonal Antibody offers researchers the ability to investigate the role of Nestin in processes such as neuronal development, brain injury, and neurodegenerative diseases. Understanding the expression and function of Nestin can provide valuable insights into the mechanisms underlying neural stem cell differentiation and regeneration, ultimately leading to potential therapeutic strategies for treating neurological disorders.
Product Name:
Nestin Rabbit Polyclonal Antibody
SKU:
CAB11861
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 1392-1621 of human NES (NP_006608.1).
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
Purification Method:
Affinity purification
Gene ID:
10763
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Neuro-2a cells, using Nestin Rabbit pAb (CAB11861) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.