The NEMF Polyclonal Antibody (PAC021693) is a valuable tool for researchers studying NEMF, a protein involved in cellular processes related to protein translation and quality control. Raised in rabbits, this antibody is highly specific to human NEMF samples and has been validated for use in Western blot applications. By targeting the NEMF protein, this antibody allows for the detection and analysis of NEMF in various cell types, making it ideal for studies in molecular biology and protein regulation.
NEMF, also known as ribosome-associated quality control protein, plays a crucial role in maintaining protein homeostasis within cells by monitoring and degrading defective proteins. Dysregulation of NEMF has been implicated in various diseases, including neurodegenerative disorders and cancer. Research into the function and regulation of NEMF is essential for developing targeted therapies aimed at correcting protein quality control mechanisms and treating associated diseases.
Antibody Name:
NEMF Antibody (PACO21693)
Antibody SKU:
PACO21693
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human SDCG1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HUVEC cells, using SDCG1 antibody.
Background:
Plays a role in nuclear export. Scanlan M.J., Int. J. Cancer 76:652-658(1998).
Synonyms:
NY-CO-1; SDCG1; serologically defined colon cancer antigen 1;
UniProt Protein Function:
SDCCAG1: Plays a role in nuclear export. Belongs to the NEMF family. 5 isoforms of the human protein are produced by alternative splicing.
