The NEMF Polyclonal Antibody (PACO20412) is a valuable tool for researchers studying NEMF, a protein involved in mRNA translation and quality control. This antibody, generated in rabbits, is highly specific to human samples and is ideal for use in Western blotting applications. It recognizes the NEMF protein, allowing for detection and analysis in a variety of cell types, making it a versatile tool for studies in molecular biology and cell biology.NEMF is known for its role in mRNA quality control and ribosome-associated processes, making it a key player in protein synthesis regulation.
Dysregulation of NEMF has been implicated in various diseases, including neurodegenerative disorders and cancer. By targeting NEMF, researchers can gain insight into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.Overall, the NEMF Polyclonal Antibody (PACO20412) is a reliable reagent for investigating the function of NEMF in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it a valuable tool for advancing scientific knowledge in the fields of molecular biology and biomedical research.
Gel: 6%SDS-PAGE, Lysate: 40 µg, Lane: Jurkat cells, Primary antibody: PACO20412(NEMF Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20412(NEMF Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
SDCCAG1, which called NY-CO-1, from a colon cancer cDNA library. The deduced 362-amino acid, protein contains a nuclear targeting signal. Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.
Synonyms:
nuclear export mediator factor
UniProt Protein Function:
SDCCAG1: Plays a role in nuclear export. Belongs to the NEMF family. 5 isoforms of the human protein are produced by alternative splicing.
