The NELL1 Polyclonal Antibody (CAB10358) is a valuable tool for researchers studying the NELL1 protein, which is known for its role in promoting bone formation and regeneration. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It specifically binds to the NELL1 protein, allowing for accurate detection and analysis in various cell types.NELL1 is a crucial factor in bone development and repair, making it a key target for studies in orthopedics, regenerative medicine, and skeletal biology.
By understanding the function and regulation of NELL1, researchers can work towards developing new therapies for bone-related disorders such as osteoporosis, fractures, and bone defects.Overall, the NELL1 Polyclonal Antibody is a reliable tool for investigating the functions of the NELL1 protein and advancing our knowledge in bone biology and regenerative medicine. Its high reactivity and specificity make it a valuable addition to any research lab focused on musculoskeletal health and tissue engineering.
Product Name:
NELL1 Rabbit Polyclonal Antibody
SKU:
CAB10358
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-420 of human NELL1 (NP_006148.2).
U-87MG,293T,Mouse pancreas,Rat brain,Rat small intestine
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus envelope, Secreted.
Calculated MW:
90kDa
Observed MW:
80kDa
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4745
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NELL1 antibody (CAB10358) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
