The NEK5 Polyclonal Antibody (PAC019209) is a valuable tool for researchers studying NEK5, a protein kinase that plays a crucial role in various cellular processes such as cell cycle regulation and cell proliferation. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting NEK5, researchers can study its functions and interactions in different cell types, making it an ideal choice for studies in cell biology and cancer research.NEK5, also known as NIMA-related kinase 5, is involved in regulating mitotic progression and has been implicated in the development and progression of various cancers.
Its significance in controlling cell division makes it a promising target for research aimed at understanding cancer growth and identifying potential therapeutic strategies. Investigating the role of NEK5 using this antibody can provide valuable insights into the molecular mechanisms underlying cancer progression and may lead to the development of novel treatment approaches.
Antibody Name:
NEK5 Antibody (PACO19209)
Antibody SKU:
PACO19209
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human NEK5
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19209(NEK5 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19209(NEK5 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
Nek5 (NimA-related protein kinase 5) is a 708 amino acid, protein that is related to NIMA, a protein that was originally discovered in Aspergillus nidulans and is necessary for entry into mitosis. One of several members of the Set/Thr protein kinase super family, Nek5 contains one protein kinase domain through which it catalyzes the ATP-dependent phosphorylation of target proteins. Like NIMA, Nek5 may be involved in mitotic regulation and cell cycle control.
