The NEK2 Rabbit Monoclonal Antibody (CAB6811) is a valuable tool for researchers studying NEK2, a protein kinase involved in cell cycle regulation and mitotic progression. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards NEK2 in human samples, making it ideal for applications such as Western blotting.NEK2 plays a key role in ensuring accurate chromosome segregation during cell division, making it a crucial player in maintaining genomic stability. Dysregulation of NEK2 has been implicated in various cancers, making it a promising therapeutic target for cancer treatment.
By enabling precise detection and analysis of NEK2 protein levels in different cell types, this antibody facilitates research in oncology and cell biology.The NEK2 Rabbit Monoclonal Antibody offers researchers a reliable tool to explore the functions and mechanisms of NEK2 in cell cycle control, mitosis, and cancer progression. Its high specificity and sensitivity make it a valuable asset for studies aiming to unravel the role of NEK2 in normal and pathological cellular processes.
Product Name:
NEK2 Rabbit Monoclonal Antibody
SKU:
CAB6811
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NEK2 (P51955).
Chromosome, Cytoplasm, Nucleus, Centromere, Centromere, Centrosome, Cytoskeleton, Kinetochore, Microtubule organizing center, Nucleolus, Spindle pole.
Calculated MW:
52kDa
Observed MW:
50kDa
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
4751
Clone Number:
ARC1418
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NEK2 Rabbit mAb (CAB6811) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
