The NEGR1 Polyclonal Antibody (PACO01152) is a valuable tool for researchers studying NEGR1, a cell adhesion molecule important in neural development and synaptic function. This antibody, produced in rabbits, has high specificity for human samples and is optimized for Western blot applications. By targeting the NEGR1 protein, researchers can accurately detect and analyze NEGR1 expression in various cell types, making it ideal for neuroscience and developmental biology studies.NEGR1 is known to play a crucial role in neural circuit formation and synaptic plasticity, making it a key player in brain development and function. Dysregulation of NEGR1 has been implicated in neurodevelopmental disorders and psychiatric conditions, making it a promising target for therapeutic interventions.
By investigating NEGR1 activity, researchers can gain insights into the molecular mechanisms underlying neurological diseases and potentially identify novel treatment strategies.Overall, the NEGR1 Polyclonal Antibody is a valuable tool for researchers interested in exploring the functions of NEGR1 in the nervous system and its potential implications for neurological disorders. Its high specificity and reliability make it a trusted reagent for studying NEGR1 in both basic research and clinical applications.
Antibody Name:
NEGR1 Antibody
Antibody SKU:
PACO01152
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human NEGR1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NEGR1; IGLON4; Neuronal growth regulator 1; IgLON family member 4
UniProt Protein Function:
NEGR1: May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain. Belongs to the immunoglobulin superfamily. IgLON family.Protein type: Membrane protein, GPI anchorChromosomal Location of Human Ortholog: 1p31.1Molecular Function: protein binding