Neurofilament M Rabbit Polyclonal Antibody (CAB16405)
- SKU:
- CAB16405
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Neurofilament M Rabbit Polyclonal Antibody |
SKU: | CAB16405 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human Neurofilament M (NP_005373.2). |
Sequence: | NEKE QLQG LNDR FAGY IEKV HYLE QQNK EIEA EIQA LRQK QASH AQLG DAYD QEIR ELRA TLEM VNHE KAQV QLDS DHLE EDIH RLKE RFEE EARL RDDT EAAI RALR KDIE EASL VKVE LDKK VQSL QDEV AFLR SNHE EEVA DLLA QIQA SHIT VERK D |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NFM; NEF3; NF-M; Neurofilament M |
Positive Sample: | SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | axon, cytoplasm, intermediate filament cytoskeleton, neurofilament, postsynaptic intermediate filament cytoskeleton |
Calculated MW: | 102kDa |
Observed MW: | 160kDa |
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4741 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |