The NEDD9 Polyclonal Antibody (CAB2521) is a valuable tool for researchers studying the protein NEDD9, which plays a critical role in cell migration and invasion. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to NEDD9, this antibody enables accurate detection and analysis of the protein in a variety of cell types, making it an essential tool for studies in cancer research and understanding cellular migration mechanisms.NEDD9, also known as neural precursor cell expressed developmentally down-regulated protein 9, is essential for promoting cell migration and invasion, processes that are often dysregulated in cancer metastasis.
By studying the function of NEDD9, researchers can gain valuable insight into the molecular mechanisms underlying cancer progression and potentially identify new therapeutic targets for cancer treatment. The NEDD9 Polyclonal Antibody is a valuable resource for researchers looking to advance our understanding of cancer biology and develop new strategies for combating this disease.
Product Name:
NEDD9 Rabbit Polyclonal Antibody
SKU:
CAB2521
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 390-560 of human NEDD9 (NP_006394.1).
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4739
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using NEDD9 Rabbit pAb (CAB2521) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
