The NEDD8 Polyclonal Antibody (CAB1163) is a valuable tool for researchers studying the NEDD8 protein, an important regulator of protein degradation and cellular processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.NEDD8, a member of the ubiquitin-like protein family, plays a crucial role in protein modification and degradation pathways. Dysregulation of NEDD8 has been implicated in various diseases, including cancer and neurodegenerative disorders, making it an attractive target for therapeutic interventions.
By binding specifically to the NEDD8 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for research in areas such as oncology, neurobiology, and cell biology. Understanding the role of NEDD8 in cellular processes is key to developing targeted therapies for diseases associated with its dysregulation.
Product Name:
NEDD8 Rabbit Polyclonal Antibody
SKU:
CAB1163
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-81 of human NEDD8 (NP_006147.1).
Enables ubiquitin protein ligase binding activity. Acts upstream of or within protein neddylation. Located in cytosol and nucleoplasm. Biomarker of Parkinson's disease and malignant astrocytoma.
Purification Method:
Affinity purification
Gene ID:
4738
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NEDD8 Rabbit pAb (CAB1163) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
