NEDD4 Rabbit Monoclonal Antibody (CAB4385)
- SKU:
- CAB4385
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NEDD4-1
- RPF1
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | NEDD4 Rabbit Monoclonal Antibody |
SKU: | CAB4385 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1200-1300 of human NEDD4 (P46934). |
Sequence: | GDVD VNDW REHT KYKN GYSA NHQV IQWF WKAV LMMD SEKR IRLL QFVT GTSR VPMN GFAE LYGS NGPQ SFTV EQWG TPEK LPRA HTCF NRLD LPPY ESFE E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | RPF1; NEDD4-1; NEDD4 |
Positive Sample: | HeLa,SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Peripheral membrane protein. |
Calculated MW: | 149kDa |
Observed MW: | 140kDa |
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Purification Method: | Affinity purification |
Gene ID: | 4734 |
Clone Number: | ARC0992 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |