NEDD4 Rabbit Polyclonal Antibody (CAB0552)
- SKU:
- CAB0552
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | NEDD4 Rabbit Polyclonal Antibody |
SKU: | CAB0552 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-460 of human NEDD4 (NP_940682.2). |
Sequence: | GSYS SNGS DFGS CASI TSGG SYTN SVIS DSSS YTFP PSDD TFLG GNLP SDST SNRS VPNR NTTP CEIF SRST STDP FVQD DLEH GLEI MKLP VSRN TKIP LKRY SSLV IFPR SPST TRPT SPTS LCTL LSKG SYQT SHQF IISP SEIA HNED GTSA KGFL STAV NGLR LSKT ICTP GEVR DIRP LHRK GSLQ KKIV LSNN TPRQ TVCE KSSE GYSC VSVH FTQR KAAT LDCE TTNG DCKP EMSE IKLN SDSE YIKL MHRT SACL PSSQ NVDC QINI NGEL ERPH SQMN KNHG ILRR SISL G |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | RPF1; NEDD4-1; NEDD4 |
Positive Sample: | U-251MG,HeLa,Jurkat,A-549,SKOV3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Peripheral membrane protein. |
Calculated MW: | 149kDa |
Observed MW: | 120kDa |
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Purification Method: | Affinity purification |
Gene ID: | 4734 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |