The NECAP2 Polyclonal Antibody (CAB14346) is a valuable tool for researchers studying NECAP2, a protein involved in regulating endocytosis and vesicle trafficking. This antibody, generated in rabbits, is highly specific to NECAP2 in human samples and has been validated for use in Western blot applications. By binding to NECAP2, this antibody allows for the detection and analysis of NECAP2 levels in various cell types, making it ideal for research in cell biology and intracellular trafficking.NECAP2 is known to play a crucial role in the internalization of cell surface receptors and the recycling of endocytic vesicles, making it an important target for studying cellular processes like receptor signaling and membrane dynamics.
Understanding the function of NECAP2 can provide valuable insights into diseases related to endocytosis dysfunction, such as neurodegenerative disorders and cancer. By using the NECAP2 Polyclonal Antibody, researchers can uncover the mechanisms underlying these diseases and potentially develop targeted therapies.
Product Name:
NECAP2 Rabbit Polyclonal Antibody
SKU:
CAB14346
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 194-263 of human NECAP2 (NP_060560.1).
This gene likely encodes a member of the adaptin-ear-binding coat-associated protein family. Studies of a similar protein in rat suggest a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
55707
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NECAP2 Rabbit pAb (CAB14346) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
