NECAB3 Rabbit Polyclonal Antibody (CAB15500)
- SKU:
- CAB15500
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NECAB3 Rabbit Polyclonal Antibody |
SKU: | CAB15500 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-362 of human NECAB3 (NP_112508.3). |
Sequence: | MACA GLLT VCLL RPPA PQPQ PQTP RHPQ LAPD PGPA GHTL FQDV FRRA DKND DGKL SFEE FQNY FADG VLSL GELQ ELFS GIDG HLTD NLET EKLC DYFS EHLG VYRP VLAA LESL NRAV LAAM DATK LEYE RASK VDQF VTRF LLRE TVSQ LQAL QSSL EGAS DTLE AQAH GWRS DAES VEAQ SRLC GSRR AGRR ALRS VSRS STWS PGSS DTGR SSEA EMQW RLQV NRLQ ELID QLEC KAPR LEPL REED LAKG PDLH ILMA QRQV QVAE EGLQ DFHR ALRC YVDF TGAQ SHCL HVSA QKML DGAS FTLY EFWQ DEAS WRRH QQSP GSKA FQRI LIDH LRAP DTLT TVFF PASW WIMN NN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | NIP1; XB51; STIP3; EFCBP3; SYTIP2; APBA2BP; dJ63M2.4; dJ63M2.5; NECAB3 |
Positive Sample: | LO2,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus. |
Calculated MW: | 44kDa |
Observed MW: | 50kDa |
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 63941 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |