NDUFV1 Rabbit Polyclonal Antibody (CAB13333)
- SKU:
- CAB13333
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | NDUFV1 Rabbit Polyclonal Antibody |
SKU: | CAB13333 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NDUFV1 (NP_009034.2). |
Sequence: | MLAT RRLL GWSL PARV SVRF SGDT TAPK KTSF GSLK DEDR IFTN LYGR HDWR LKGS LSRG DWYK TKEI LLKG PDWI LGEI KTSG LRGR GGAG FPTG LKWS FMNK PSDG RPKY LVVN ADEG EPGT CKDR EILR HDPH KLLE GCLV GGRA MGAR AAYI YIRG EFYN EASN LQVA IREA YEAG LIGK NACG SGYD FDVF VVRG AGAY ICGE ETAL IESI EGKQ GKPR LKPP FPAD VGVF GCPT TVAN VETV AV |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | UQOR1; CI-51K; CI51KD; MC1DN4; NDUFV1 |
Positive Sample: | Mouse kidney,Rat brain,Rat spinal cord |
Conjugate: | Unconjugated |
Cellular Localization: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein. |
Calculated MW: | 51kDa |
Observed MW: | 51kDa |
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4723 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |