The NDUFs3 Rabbit Monoclonal Antibody (CAB4602) is a specialized research tool designed for the detection and analysis of NDUFs3 protein in various cell types. NDUFs3, a subunit of mitochondrial complex I, is crucial in the electron transport chain and ATP production. The antibody, produced in rabbits, is highly specific and reactive with human samples, validated for use in Western blot applications.NDUFs3 is essential for cellular energy production and metabolic function, making it a key player in mitochondrial function and overall cell health. Dysfunction of NDUFs3 is linked to various diseases, including mitochondrial disorders, neurodegenerative diseases, and metabolic syndromes.
By targeting NDUFs3, researchers can gain valuable insights into mitochondrial dysfunction and its implications in disease pathology.This NDUFs3 Rabbit Monoclonal Antibody is a reliable tool for investigating the role of NDUFs3 in mitochondrial function and disease pathogenesis. Its high specificity and reactivity make it suitable for various research applications in the fields of cell biology, biochemistry, and mitochondrial physiology. Whether studying basic cellular mechanisms or exploring potential therapeutic targets, this antibody is an essential tool for researchers in the field.
Product Name:
NDUFS3 Rabbit Monoclonal Antibody
SKU:
CAB4602
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 165-264 of human NDUFS3 (O75489).
This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
Purification Method:
Affinity purification
Gene ID:
4722
Clone Number:
ARC1049
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDUFS3 Rabbit mAb (CAB4602) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
