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NDUFS1 Rabbit Polyclonal Antibody (CAB16926)

SKU:
CAB16926
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 7 Anti-NDUFS1 Antibody CAB16926
  • Cell Biology Antibodies 7 Anti-NDUFS1 Antibody CAB16926
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NDUFS1 Rabbit Polyclonal Antibody
SKU:CAB16926
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-290 of human NDUFS1 (NP_004997.4).
Sequence:VEIE KAPK VVAA CAMP VMKG WNIL TNSE KSKK AREG VMEF LLAN HPLD CPIC DQGG ECDL QDQS MMFG NDRS RFLE GKRA VEDK NIGP LVKT IMTR CIQC TRCI RFAS EIAG VDDL GTTG RGND MQVG TYIE KMFM SELS GNII DICP VGAL TSKP YAFT ARPW ETRK TESI DVMD AVGS NIVV STRT GEVM RILP RMHE DINE EWIS DKT
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:CI-75k; MC1DN5; CI-75Kd; PRO1304; NDUFS1
Positive Sample:Raji,NCI-H460,PC-3,Mouse heart,Mouse intestine
Cellular Localization:Mitochondrion inner membrane.
Calculated MW:79kDa
Observed MW:75kDa

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:4719
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using NDUFS1 Rabbit pAb (CAB16926) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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