The NDUFC2 Polyclonal Antibody is a vital tool for researchers investigating NDUFC2, a critical component of complex I in the electron transport chain. This antibody, produced in rabbits, boasts high specificity and sensitivity for human samples, making it an excellent choice for Western blot applications. By targeting the NDUFC2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable resource for studies in bioenergetics and mitochondrial function.
NDUFC2 is essential for the proper functioning of complex I, which is responsible for generating the majority of ATP in the cell through oxidative phosphorylation. Mutations in NDUFC2 have been linked to various mitochondrial disorders and metabolic diseases, highlighting its importance in cellular energy production. By understanding the role of NDUFC2, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.
Product Name:
NDUFC2 Polyclonal Antibody
SKU:
CAB3312
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NDUFC2 (NP_004540.1).
Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Part of mitochondrial respiratory chain complex I. Implicated in nuclear type mitochondrial complex I deficiency.
Purification Method:
Affinity purification
Gene ID:
4718
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using NDUFC2 Rabbit pAb (CAB3312).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
