The NDUFB8 Monoclonal Antibody (CAB19732) is a powerful tool for research involving the NDUFB8 protein, a key subunit of the mitochondrial respiratory complex I. This monoclonal antibody, developed through immunization of mice, exhibits high specificity for human samples and has been validated for use in various applications, including Western blotting. By targeting the NDUFB8 protein, this antibody enables accurate detection and analysis of mitochondrial complex I activity in different cell types, making it an essential component for studies in bioenergetics, mitochondrial dysfunction, and related diseases.The NDUFB8 protein is essential for the proper function of complex I, which is a central player in cellular energy production through oxidative phosphorylation.
Dysfunction in complex I has been linked to a variety of human diseases, including neurodegenerative disorders, metabolic disorders, and aging-related conditions. By studying the role of NDUFB8 in mitochondrial function, researchers can gain valuable insights into the mechanisms underlying these diseases and potential therapeutic targets for intervention. Using the NDUFB8 Monoclonal Antibody, scientists can further our understanding of mitochondrial biology and its implications for human health.
Product Name:
NDUFB8 Rabbit Monoclonal Antibody
SKU:
CAB19732
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human NDUFB8 (O95169).
Involved in mitochondrial respiratory chain complex I assembly. Located in endoplasmic reticulum and mitochondrion. Part of mitochondrial respiratory chain complex I. Implicated in nuclear type mitochondrial complex I deficiency 32. Biomarker of Alzheimer's disease and Parkinson's disease.
Purification Method:
Affinity purification
Gene ID:
4714
Clone Number:
ARC2259
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDUFB8 Rabbit mAb (CAB19732) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
