The NDUFB7 Polyclonal Antibody (CAB13693) is a valuable tool for researchers studying NDUFB7, a subunit of the mitochondrial respiratory complex I involved in energy production. This antibody, produced in rabbits, exhibits high specificity for human samples and is suitable for Western blot applications. By targeting the NDUFB7 protein, this antibody enables precise detection and analysis in a variety of cell types, making it essential for investigations in the fields of bioenergetics and mitochondrial function.
NDUFB7 plays a crucial role in the electron transport chain, a key process in energy metabolism essential for cell survival and function. Dysregulation of complex I subunits like NDUFB7 has been implicated in a variety of diseases, including mitochondrial disorders and neurodegenerative conditions. Therefore, studying the function and expression of NDUFB7 is essential for gaining insights into these pathologies and developing potential therapeutic strategies targeting mitochondrial dysfunction.
Product Name:
NDUFB7 Rabbit Polyclonal Antibody
SKU:
CAB13693
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human NDUFB7 (NP_004137.2).
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It is located at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Purification Method:
Affinity purification
Gene ID:
4713
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDUFB7 Rabbit pAb (CAB13693) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
