The NDUFB11 Polyclonal Antibody (CAB15617) is a valuable tool for research involving NDUFB11, a subunit of mitochondrial respiratory complex I involved in electron transport. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples and has been tested for use in Western blot applications. By targeting the NDUFB11 protein, researchers can detect and analyze its expression in various cell types, providing insights into mitochondrial function and cellular metabolism.NDUFB11 is essential for the proper functioning of complex I, which is responsible for generating the majority of cellular ATP through oxidative phosphorylation. Dysregulation of complex I activity has been linked to various human diseases, including neurodegenerative disorders and metabolic syndromes.
By studying NDUFB11, researchers can gain a better understanding of mitochondrial dysfunction and its implications for health and disease.The NDUFB11 Polyclonal Antibody is a valuable tool for investigating the role of mitochondrial complex I in cellular physiology and pathology. Its specificity and sensitivity make it an ideal choice for researchers studying mitochondrial function, energy metabolism, and related disorders. By utilizing this antibody in their studies, scientists can advance our understanding of complex I biology and potentially uncover new therapeutic targets for a range of diseases.
Product Name:
NDUFB11 Rabbit Polyclonal Antibody
SKU:
CAB15617
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human NDUFB11 (NP_061929.2).
mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion
Calculated MW:
17kDa
Observed MW:
17kDa
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is located at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to ubiquinone. Mutations in the human gene are associated with linear skin defects with multiple congenital anomalies 3 and mitochondrial complex I deficiency.
Purification Method:
Affinity purification
Gene ID:
54539
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDUFB11 Rabbit pAb (CAB15617) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
