The NDUFAF5 Polyclonal Antibody (CAB7135) is a valuable tool for researchers studying the NDUFAF5 protein, a key component of mitochondrial complex I involved in oxidative phosphorylation. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By targeting the NDUFAF5 protein, this antibody allows for the analysis and detection of NDUFAF5 in various cell types, making it ideal for investigations in mitochondrial biology and metabolic diseases.NDUFAF5 is essential for maintaining mitochondrial function and energy production, making it a crucial target for research on conditions such as mitochondrial disorders, metabolic diseases, and neurodegenerative disorders.
By understanding the role of NDUFAF5 in mitochondrial function, researchers can gain insight into potential therapeutic strategies for these diseases. The NDUFAF5 Polyclonal Antibody is a valuable tool for studies aimed at unraveling the molecular mechanisms underlying mitochondrial dysfunction and metabolic disorders.
Product Name:
NDUFAF5 Rabbit Polyclonal Antibody
SKU:
CAB7135
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 196-345 of human NDUFAF5 (NP_077025.2).
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes a mitochondrial protein that is associated with the matrix face of the mitochondrial inner membrane and is required for complex I assembly. A mutation in this gene results in mitochondrial complex I deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
79133
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NDUFAF5 antibody (CAB7135) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
