The NDUFAF1 Polyclonal Antibody is a valuable tool for researchers studying the NDUFAF1 protein, a critical component of the mitochondrial respiratory chain complex I. This antibody, generated in rabbits, exhibits high specificity and sensitivity when used in Western blot applications with human samples. By binding to NDUFAF1, it enables the detection and analysis of this protein in various cell types, making it ideal for studies in mitochondrial biology and metabolic disorders.NDUFAF1 is essential for the assembly and function of complex I in the electron transport chain, playing a key role in generating cellular energy through oxidative phosphorylation.
Dysregulation of NDUFAF1 has been implicated in various diseases, including mitochondrial disorders and neurodegenerative conditions. Investigating the function and expression of NDUFAF1 with this antibody can provide valuable insights into the pathophysiology of these disorders and potential therapeutic targets.Overall, the NDUFAF1 Polyclonal Antibody offers researchers a reliable tool for studying the function of the NDUFAF1 protein in various physiological and pathological contexts, advancing our understanding of mitochondrial metabolism and its implications for human health.
Product Name:
NDUFAB1 Polyclonal Antibody
SKU:
CAB22019
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-156 of human NDUFAB1 (NP_004994.1).
Predicted to enable acyl binding activity; acyl carrier activity; and fatty acid binding activity. Involved in mitochondrial respiratory chain complex I assembly and protein lipoylation. Located in mitochondrion and nucleoplasm. Part of mitochondrial respiratory chain complex I. Colocalizes with mitochondrial large ribosomal subunit.
Purification Method:
Affinity purification
Gene ID:
4706
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NDUFAB1 antibody (CAB22019) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
