The NDUFA8 Polyclonal Antibody (CAB12118) is a versatile tool designed for researchers studying NDUFA8, a subunit of the mitochondrial respiratory chain complex I. This antibody, produced in rabbits, exhibits high reactivity specifically with human samples and is validated for use in Western blot applications.NDUFA8 is a key player in mitochondrial energy production and function, making it a crucial target for research on metabolic disorders, neurodegenerative diseases, and cancer. By detecting and analyzing NDUFA8 levels in various cell types, this antibody enables researchers to gain insights into the role of this protein in cellular energetics and disease pathogenesis.
With its reliability and specificity in detecting NDUFA8 protein, this polyclonal antibody is an essential tool for advancing our understanding of mitochondrial function and its implications in health and disease. It is an invaluable resource for researchers in the fields of biochemistry, cell biology, and mitochondrial physiology.
Product Name:
NDUFA8 Rabbit Polyclonal Antibody
SKU:
CAB12118
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-172 of human NDUFA8 (NP_055037.1).
The protein encoded by this gene belongs to the complex I 19 kDa subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
4702
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDUFA8 Rabbit pAb (CAB12118) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
