The NDUFA13 Polyclonal Antibody (CAB5412) is a valuable tool for researchers studying NDUFA13, a subunit of the mitochondrial respiratory chain complex I involved in energy production. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting NDUFA13 in human samples, making it ideal for Western blot applications. By targeting the NDUFA13 protein, researchers can gain insights into mitochondrial function and its potential role in various biological processes.NDUFA13 is a key player in cellular respiration, playing a crucial role in converting nutrients into energy through oxidative phosphorylation.
Dysregulation of NDUFA13 has been implicated in various diseases, including mitochondrial disorders and neurodegenerative conditions. Studying NDUFA13 with this antibody can provide valuable information for understanding the mechanisms underlying these diseases and potentially identifying new therapeutic strategies.Overall, the NDUFA13 Polyclonal Antibody (CAB5412) offers researchers a reliable tool for investigating the function of NDUFA13 and its implications in health and disease. Its versatility and specificity make it a valuable asset for studies in mitochondrial biology, energy metabolism, and related fields of research.
Product Name:
NDUFA13/GRIM19 Rabbit Polyclonal Antibody
SKU:
CAB5412
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human NDUFA13/GRIM19 (NP_057049.5).
This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
51079
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using [KD Validated] NDUFA13/GRIM19 Rabbit pAb (CAB5412) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
