The NDUFA11 Polyclonal Antibody (CAB16239) is a valuable tool for research involving NDUFA11, a subunit of NADH:ubiquinone oxidoreductase complex I, a key enzyme in the electron transport chain. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the NDUFA11 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies in bioenergetics and mitochondrial function.NDUFA11 is essential for the function of complex I in the mitochondrial respiratory chain, playing a crucial role in producing cellular energy through oxidative phosphorylation.
Dysregulation of NDUFA11 has been linked to a variety of diseases, including neurodegenerative disorders, metabolic disorders, and cancer. Understanding the function of NDUFA11 is vital for unraveling the molecular mechanisms underlying these conditions and developing targeted therapies.Overall, the NDUFA11 Polyclonal Antibody (CAB16239) is a reliable tool for researchers investigating the role of NDUFA11 in cellular metabolism and disease progression. Its high specificity and sensitivity make it a valuable asset in the quest for new insights into mitochondrial function and its implications for human health.
Product Name:
NDUFA11 Rabbit Polyclonal Antibody
SKU:
CAB16239
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NDUFA11 (NP_783313.1).
mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion
Calculated MW:
15kDa
Observed MW:
15kDa
This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
126328
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDUFA11 Rabbit pAb (CAB16239) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
