The NDUFA10 Polyclonal Antibody (CAB10123) is a valuable tool for research involving NDUFA10, a critical subunit of the mitochondrial respiratory chain complex I. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the NDUFA10 protein, researchers can confidently detect and study this essential component in various cell types, making it ideal for investigations in bioenergetics, mitochondrial dysfunction, and metabolic diseases.NDUFA10 is a key player in the electron transport chain, facilitating the transfer of electrons and the generation of ATP for cellular energy production.
Dysregulation of NDUFA10 has been implicated in various diseases, including mitochondrial disorders, neurodegenerative conditions, and metabolic syndromes. By studying the function and expression of NDUFA10, researchers can gain insights into the mechanisms underlying these pathologies and potentially identify new therapeutic targets for intervention.Overall, the NDUFA10 Polyclonal Antibody offers researchers a reliable tool for investigating the role of NDUFA10 in mitochondrial function and cellular metabolism, paving the way for advancements in understanding and treating a wide range of diseases associated with mitochondrial dysfunction.
Product Name:
NDUFA10 Rabbit Polyclonal Antibody
SKU:
CAB10123
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human NDUFA10 (NP_004535.1).
The protein encoded by this gene is a component of 42 kDa complex I, the first enzyme complex in the electron transport chain of mitochondria. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. A mutation in this gene was found in an individual with Leigh syndrome.
Purification Method:
Affinity purification
Gene ID:
4705
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NDUFA10 antibody (CAB10123) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
