NDUFA1 Rabbit Polyclonal Antibody (CAB8326)
- SKU:
- CAB8326
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | NDUFA1 Rabbit Polyclonal Antibody |
SKU: | CAB8326 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human NDUFA1 (NP_004532.1). |
Sequence: | MWFE ILPG LSVM GVCL LIPG LATA YIHR FTNG GKEK RVAH FGYH WSLM ERDR RISG VDRY YVSK GLEN ID |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MWFE; ZNF183; CI-MWFE; MC1DN12; NDUFA1 |
Positive Sample: | MCF-7,Mouse kidney,Mouse heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Matrix side, Mitochondrion inner membrane, Single-pass membrane protein. |
Calculated MW: | 8kDa |
Observed MW: | 14kDa |
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.
Purification Method: | Affinity purification |
Gene ID: | 4694 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |