The NDRG4 Polyclonal Antibody (CAB16195) is a valuable tool for researchers studying NDRG4, a protein that plays a key role in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the NDRG4 protein, this antibody enables the accurate detection and analysis of NDRG4 in different cell types, making it an ideal choice for studies in cell biology and cancer research.
NDRG4, also known as N-Myc downstream regulated gene 4, is involved in the regulation of cell growth, differentiation, and stress responses. Its dysregulation has been implicated in various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. By studying the role of NDRG4 in these conditions, researchers can gain valuable insights into disease mechanisms and potentially identify novel therapeutic targets for treatment.
Product Name:
NDRG4 Rabbit Polyclonal Antibody
SKU:
CAB16195
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-220 of human NDRG4 (NP_001229765.1).
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
65009
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDRG4 Rabbit pAb (CAB16195) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
