NDRG1 Monoclonal Antibody [PAT11G4AT] (CPAB0649)
- SKU:
- CPAB0649
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT11G4AT
- Applications:
- ELISA
- FC
Description
NDRG1 Monoclonal Antibody [PAT11G4AT] (CPAB0649)
Based on the information provided in the URL https://www.assaygenie.com/ndrg1-antibody-cpab0649/, we have the NDRG1 Polyclonal Antibody (CPAB0649). This antibody is specifically designed for research involving NDRG1, a protein that plays a crucial role in various cellular processes such as cell growth, differentiation, and stress responses. The NDRG1 Polyclonal Antibody (CPAB0649) is raised in rabbits and has been validated for use in Western blot applications. It shows high reactivity with human samples, enabling accurate detection and analysis of the NDRG1 protein in a variety of cell types.
This makes it an ideal tool for researchers in the fields of cancer biology, cell biology, and molecular biology.NDRG1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Understanding the function and regulation of NDRG1 is essential for developing targeted therapies for these conditions. The NDRG1 Polyclonal Antibody (CPAB0649) provides researchers with a valuable tool to study the role of NDRG1 in health and disease, ultimately leading to advancements in clinical treatments and therapies.
| Product Name: | NDRG1 Antibody |
| Product Sku: | CPAB0649 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human NDRG1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NDRG1 protein 1-394 amino acids purified from Ecoli. |
| Clone: | PAT11G4AT. |
| Reactivity: | Other bodies |
| Applications: | ELISA, Flow Cytometry |
| Purification Method: | NDRG1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is one of 4 members of the NDRG ?/?-hydrolase family. NDRG1 is classified in databases as a tumor suppressor and heavy metal-response protein. NDRG1€™s functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. NDRG1 is also essential for p53-mediated caspase activation and apoptosis. The NDRG1 is a Rab4a effector that is involved in vesicular recycling of E-cadherin. NDRG1 is ubiquitous; it is expressed most notably in placental membranes and prostate, kidney, small intestine, and ovary tissues. NDRG1 has reduced expression in adenocarcinomas compared to normal tissues. NDRG1 gene mutations are reported to be the cause for hereditary motor and sensory neuropathy-Lom (HMSNL), which is a severe autosomal recessive form of Charcot- Marie-Tooth (CMT) disease. In addition, decreased NDRG1 expression in glioma is linked to tumor progression. On the other hand, overexpression of NDRG1 is connected to malignant status of esophageal cancer. NDRG1 may also have a role in portal vein invasion and intrahepatic metastasis in human hepatocellular carcinoma. |
| Synonyms: | Protein NDRG1, N-myc downstream-regulated gene 1 protein, Differentiation-related gene 1 protein, Reducing agents and tunicamycin-responsive protein, Nickel-specific induction protein Cap43, DRG-1, RTP, Rit42, NDRG1, CAP43, DRG1, GC4, NDR1, NMSL, TDD5, CMT4D, HMSNL, TARG1, PROXY1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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