The NDP52 Monoclonal Antibody is a powerful tool for researchers studying the intracellular protein NDP52, which plays a key role in autophagy and innate immune response. This antibody, generated through mouse hybridoma technology, is highly specific to NDP52 and has been validated for use in various immunoassays, such as immunofluorescence and immunoprecipitation. NDP52 is a critical mediator of selective autophagy, targeting intracellular pathogens for degradation and promoting immune defense mechanisms.
Its involvement in antimicrobial responses and cellular homeostasis makes it a promising target for investigating infectious diseases, inflammatory disorders, and cancer progression. By utilizing the NDP52 Monoclonal Antibody, researchers can gain valuable insights into the molecular mechanisms underlying autophagy and immune defense pathways.
Product Name:
NDP52 Monoclonal Antibody
SKU:
CAB24021
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human NDP52 (NP_005822.1).
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10241
Clone Number:
ARC54603
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using NDP52 Rabbit mAb (CAB24021) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
