NDE1 Rabbit Polyclonal Antibody (CAB14136)
- SKU:
- CAB14136
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | NDE1 Rabbit Polyclonal Antibody |
SKU: | CAB14136 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human NDE1 (NP_060138.1). |
Sequence: | MEDS GKTF SSEE EEAN YWKD LAMT YKQR AENT QEEL REFQ EGSR EYEA ELET QLQQ IETR NRDL LSEN NRLR MELE TIKE KFEV QHSE GYRQ ISAL EDDL AQTK AIKD QL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | NDE; LIS4; MHAC; NUDE; NUDE1; HOM-TES-87; NDE1 |
Positive Sample: | HeLa,HepG2,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cleavage furrow, Cytoplasm, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle. |
Calculated MW: | 38kDa |
Observed MW: | 39kDa |
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 54820 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |