HEC1/NDC80 Rabbit Polyclonal Antibody (CAB5411)
- SKU:
- CAB5411
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | HEC1/NDC80 Rabbit Polyclonal Antibody |
SKU: | CAB5411 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 343-642 of human HEC1/HEC1/NDC80 (NP_006092.1). |
Sequence: | ETIK QENT RLQN IIDN QKYS VADI ERIN HERN ELQQ TINK LTKD LEAE QQKL WNEE LKYA RGKE AIET QLAE YHKL ARKL KLIP KGAE NSKG YDFE IKFN PEAG ANCL VKYR AQVY VPLK ELLN ETEE EINK ALNK KMGL EDTL EQLN AMIT ESKR SVRT LKEE VQKL DDLY QQKI KEAE EEDE KCAS ELES LEKH KHLL ESTV NQGL SEAM NELD AVQR EYQL VVQT TTEE RRKV GNNL QRLL EMVA THVG SVEK HLEE QIAK VDRE YEEC MSED LSEN IKEI RDKY EKKA TLIK SSEE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80; HEC1/NDC80 |
Positive Sample: | K-562,Lovo,MCF7,22Rv1,THP-1,293T,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, centromere, kinetochore. |
Calculated MW: | 74kDa |
Observed MW: | 80kDa |
This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.
Purification Method: | Affinity purification |
Gene ID: | 10403 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |