The ND5 Polyclonal Antibody (CAB12465) is a valuable tool for researchers studying ND5, a subunit of the mitochondrial respiratory chain complex I involved in energy production. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in various applications, including Western blot and immunohistochemistry.By specifically targeting the ND5 protein, this antibody enables researchers to analyze mitochondrial function and investigate the role of ND5 in energy metabolism and cellular respiration.
Its utility in studying mitochondrial dysfunction and related diseases, such as metabolic disorders and neurodegenerative conditions, make it an essential component of research in the fields of biochemistry and molecular biology. Overall, the ND5 Polyclonal Antibody is a reliable tool for researchers seeking to uncover the intricacies of mitochondrial function and its impact on cellular health and disease pathology.
Product Name:
MT-ND5 Rabbit Polyclonal Antibody
SKU:
CAB12465
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of mouse MT-ND5 (NP_904338.1).
Contributes to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in central nervous system; heart; liver; metanephros; and retina. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Orthologous to human MT-ND5 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5).
Purification Method:
Affinity purification
Gene ID:
17721
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MT-ND5 antibody (CAB12465) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
