The NCS1 Polyclonal Antibody (CAB6455) is a powerful tool for researchers studying the NCS1 protein, a key player in calcium signaling and neurotransmitter release. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting NCS1 in human samples, making it ideal for use in various experimental techniques such as Western blotting.NCS1, also known as neuronal calcium sensor 1, is involved in regulating intracellular calcium levels in neurons and is essential for proper neuronal function and communication.
Dysregulation of NCS1 has been implicated in various neurological disorders, making it a promising target for therapeutic interventions.By using the NCS1 Polyclonal Antibody, researchers can gain valuable insights into the role of NCS1 in neuronal signaling pathways and its potential implications in neurological diseases. This antibody offers a reliable tool for investigating the function and regulation of NCS1, paving the way for new discoveries in the field of neuroscience.
Product Name:
NCS1 Rabbit Polyclonal Antibody
SKU:
CAB6455
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human NCS1 (NP_055101.2).
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23413
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NCS1 antibody (CAB6455) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
