The NCS1 Polyclonal Antibody (CAB0598) is a valuable tool for researchers studying NCS1, a calcium-binding protein involved in various cellular processes such as neurotransmission and synaptic plasticity. This antibody, generated in rabbits, exhibits high specificity in detecting NCS1 protein in human samples, making it suitable for use in Western blotting experiments.NCS1, also known as neuronal calcium sensor 1, is essential for regulating calcium signaling in neurons and plays a crucial role in neuronal function and development. Dysregulation of NCS1 has been implicated in neurological disorders such as schizophrenia and bipolar disorder, making it a key target for further investigation in neuroscience research.
By utilizing the NCS1 Polyclonal Antibody in their studies, researchers can gain valuable insights into the function and regulation of NCS1 in neuronal cells, leading to a better understanding of its role in neurological disorders and potential therapeutic interventions. This antibody is a valuable tool for advancing research in neuroscience and neurology.
Product Name:
NCS1 Rabbit Monoclonal Antibody
SKU:
CAB0598
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 91-190 of human NCS1 (P62166).
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23413
Clone Number:
ARC2523
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using NCS1 antibody (CAB0598) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.