NCR3LG1 Antibody (PACO46638)
- SKU:
- PACO46638
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
NCR3LG1 Antibody (PACO46638)
The NCR3LG1 Polyclonal Antibody (PACO46638) is a vital tool for researchers studying NCR3LG1, a cell surface molecule with implications in immune regulation. This antibody, developed in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the NCR3LG1 protein, researchers can detect and analyze its expression in various cell types, making it an ideal tool for studies in immunology, cancer research, and beyond.NCR3LG1, also known as a member of the natural cytotoxicity triggering receptor family, plays a crucial role in immune response modulation by regulating inflammation and inhibiting allergic reactions.
Its involvement in immune homeostasis makes it a promising target for research into conditions such as cancer, autoimmune disorders, and chronic inflammatory diseases. A comprehensive understanding of NCR3LG1 activity is essential for the development of therapies that can leverage or modulate immune function in these contexts.
| Antibody Name: | NCR3LG1 Antibody (PACO46638) |
| Antibody SKU: | PACO46638 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Natural cytotoxicity triggering receptor 3 ligand 1 protein (25-262AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: B7H6 antibody at 2 µg/ml. Lane 1: Mouse heart tissue. Lane 2: Mouse liver tissue. Lane 3: Mouse brain tissue. Lane 4: Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51 kDa. Observed band size: 51, 38, 32 kDa.. |
 | Immunofluorescent analysis of HepG2 cells using PACO46638 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO46638 at dilution of 1:100. |
| Background: | Triggers NCR3-dependent natural killer cell activation. |
| Synonyms: | Natural cytotoxicity triggering receptor 3 ligand 1 (B7 homolog 6) (B7-H6), NCR3LG1, B7H6 |
| UniProt Protein Function: | B7-H6: Triggers NCR3-dependent natural killer cell activation. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11p15.1 Cellular Component: plasma membrane Biological Process: regulation of immune response |
| NCBI Summary: | B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011] |
| UniProt Code: | Q68D85 |
| NCBI GenInfo Identifier: | 74708829 |
| NCBI Gene ID: | 374383 |
| NCBI Accession: | Q68D85.1 |
| UniProt Secondary Accession: | Q68D85,Q7Z3M6, |
| UniProt Related Accession: | Q68D85 |
| Molecular Weight: | 50,827 Da |
| NCBI Full Name: | Natural cytotoxicity triggering receptor 3 ligand 1 |
| NCBI Synonym Full Names: | natural killer cell cytotoxicity receptor 3 ligand 1 |
| NCBI Official Symbol: | NCR3LG1Â Â |
| NCBI Official Synonym Symbols: | B7H6; B7-H6; DKFZp686O24166Â Â |
| NCBI Protein Information: | natural cytotoxicity triggering receptor 3 ligand 1 |
| UniProt Protein Name: | Natural cytotoxicity triggering receptor 3 ligand 1 |
| UniProt Synonym Protein Names: | B7 homolog 6; B7-H6 |
| Protein Family: | Natural cytotoxicity triggering receptor |
| UniProt Gene Name: | NCR3LG1Â Â |
| UniProt Entry Name: | NR3L1_HUMAN |
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